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Name of the project: Regions and (E)DIHs alliance for AI-at-the-Edge adoption by European Industry 5.0 Manufacturing SMEs

Start/end: January 2023 / December 2025

EU Contribution: 7 462 614.00




Internal contacts
Elena Mossali –

Martina Imarisio Neviani – 


43 European partners from 18 countries and 15 regions collaborate within the EU-funded AI REDGIO 5.0 project, started in January 2023. AI REDGIO 5.0 aims at renovating and extending the Horizon 2020 I4MS – AI REGIO alliance between Vanguard EU regions and DIHs for a competitive AI-at-the-Edge Digital Transformation of Industry 5.0 Manufacturing SMEs.



For the digital transformation of European Manufacturing SMEs, the ICT Innovation for Manufacturing SMEs (I4MS) program under Horizon 2020 has been a great success. Program Phase IV concentrated on Digital Innovation Hubs (DIHs) and cutting-edge technology like AI and digital twins. The AI REGIO Innovation Action, in particular, created a symbiotic partnership between regions, DIHs, AI solution providers, and manufacturing SMEs. This partnership is manifested by a new methodology for DIHs service portfolio and customer journey analysis, an AI4EU-focused toolkit of Data and AI resources, a network of Didactic Factories and their TEchnology and REgulatory SAndboxes (TERESA), an ecosystem of SME-driven experiments, and their Digital Transformation pathways.

With the aim of coordinating such significant outcomes with the evolution of manufacturing toward Industry 5.0, the evolution of cloud AI technologies to AI-at-the-Edge, the evolution of Horizon2020 to Horizon Europe , and the evolution of Digital Europe programmes such as EDIH, Data Spaces, and AI TEFs (Testing and Experimentation Facilities) for manufacturing, AI REDGIO 5.0 maintains the momentum of AI technology adoption in Manufacturing SMEs. The H2020 I4MS – AI REGIO partnership between Vanguard EU regions and DIHs will be updated and expanded as part of AI REDGIO 5.0 in order to enable competitive AI-at-the-Edge digital transformation of Industry 5.0 Manufacturing SMEs.



Within the project, AFIL is responsible of the Dissemination and Communication activities to create awareness and address manufacturing SMEs, their Innovation Hubs and tailored specific skills developments programs. Moreover, AFIL also supports the development of the AI REDGIO 5.0 network and the involvement of the regional ecosystem through the preparation, management, and execution of the Open Call process.